Evidence suggests a beneficial effect for selectively including forced reps, drop sets, supersets, and heavy negatives in a hypertrophy-oriented resistance training routine. The lack of
direct research examining the hypertrophic effect of these techniques makes it difficult to provide specific guidelines for volume and frequency. However, their fatiguing nature increases the risk for overreaching and overtraining, and it is generally prudent to limit their use to no more than a few microcycles over the course of a periodized program. That said, people have differing recuperative abilities and experimentation is therefore necessary to determine an appropriate volume and frequency for the individual. Potential signs of overtraining should be
continually monitored to optimize results.
Moreover, these techniques should be considered advanced training strategies. Their use has a taxing effect on the neuromuscular system that is likely to exceed a beginner’s capacity for adaptation. Based on the author’s experience, a minimum of several months of regimented training is warranted before integrating the techniques into a routine